English [en] · PDF · 18.1MB · 1978 · 📗 Book (unknown) · 🚀/duxiu/ia/zlib · Save
description
xxi, 468 p. : 24 cm, Papers presented at a symposium held in San Francisco, Aug. 30-Sept. 1, 1976, Includes bibliographical references and index
Alternative filename
ia/chemistrybiology0000unse_f5h5.pdf
Alternative title
Chemistry of Nucleosides and Nucleotides (Discontinued (Chemistry of Nucleosides and Nucleotides))
Alternative author
Robert E Harmon; Roland K Robins; Leroy B Townsend; American Chemical Society. Carbohydrate Division. Centennial Meeting
Alternative author
L.B. Townsend, L. B. Townsend, Roland K. Robins, Leroy B. Townsend
Alternative author
edited by Robert E. Harmon, Roland K. Robins, Leroy B. Townsend
Alternative author
Chemistry and Biology of Nucleosides and Nucleotides Conference
Alternative publisher
Academic Press, Incorporated
Alternative publisher
Morgan Kaufmann Publishers
Alternative publisher
Brooks/Cole
Alternative edition
Academic Press rapid manuscript reproduction, New York, 1978
Alternative edition
New York ; San Francisco ; London, 1978
Alternative edition
United States, United States of America
Alternative edition
New York, New York State, 1978
Alternative edition
6, 2012
metadata comments
Includes bibliographical references and index. Papers presented at a symposium held in San Francisco, Aug. 30-Sept. 1, 1976.
Alternative description
Chemistry and Biology of Nucleosides and Nucleotides is a collection of papers presented at the symposium on the Chemistry and Biology of Nucleosides and Nucleotides, held on August 30-September 1, 1976, as part of the San Francisco Centennial Meeting of the Carbohydrate Division of the American Chemical Society. Contributors explore the chemistry and biology of nucleosides and nucleotides ans well as the different chemical and instrumental techniques used in their synthesis. This book is comprised of 28 chapters and begins by describing the synthesis of a gene and its introduction into a biological system where it proved to be functional. The synthesis of nucleosides and nucleotides with anticancer and antiviral activity is also discussed, along with the rationale for the design and synthesis of such compounds. Simple models of nucleic acid interactions are described. Subsequent chapters explore the chemistry and biological activity of C-nucleosides related to pseudouridine and of some nucleoside analogs active against tumor cells; the selectivity and stereospecificity of the ribosylation reaction; synthesis of C-glycosyl thiazoles; and C-nucleoside isosteres of some nucleoside antibiotics. This monograph will serve as reference and source material for many workers in biomedical research as teaching material for instructors of advanced science courses.
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